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Mass Spectrometry

We are a service facility equipped with unique technology and experienced scientists in the field of mass spectrometry. We engage in projects of commissioned research for the research groups at the Centre for Analysis Synthesis (CAS), but also for other departments, other universities, national authorities or companies.

Services

We develop and optimize analytical methods for organic and organometallic compounds, using either liquid chromatography (UHPLC) or supercritical fluid chromatography (SFC) with MS and MS/MS characterization or quantification. Gas chromatography mass spectrometry is also available for the analysis of volatile compounds, as well as a state-of-the-art pipetting robot for automated sample preparation.

At Centre for Analysis and Synthesis we have several Mass Spectrometry systems:

Trapped ion mobility spectrometry (TIMS) combined with quadrupole time of flight mass spectrometry (Q-TOF). It can be coupled to a highly modular supercritical fluid extraction (SFE) and LC/SFC system.

This is a powerful analytical equipment used for identification of analyses in complex matrices as well as for quantitative and qualitative analysis of peptides and proteolytic digests.

TIMS-TOF (Bruker). Photo.

This sensitive and robust triple quadrupole mass spectrometer is used for analysis of low (ppb) levels of environmental compounds and biomarkers.

Routine work includes method development and optimization of LC-MS/MS methods.

Triple quadrupole mass spectrometer. Photo

This instrument is used for the characterization of synthesized or isolated organic and organometallic compounds.

Routine work includes determination of molecular formula and accurate mass with an accuracy of ± 1 mDa  of compounds with m/z up to 3000 mDa. Ionisation modes include electrospray ionization (ESI) or atmospheric pressure chemical ionization (APCI).

Xevo G2 QTof. Photo.

Contact

Annette Krais, PhD, Head of Unit

annette.krais@chem.lu.se

Kornelije Kraguljac, M.Eng.

kornelije.kraguljac@chem.lu.se

Fiona Nermark, PhD

fiona.nermark@chem.lu.se

 

Page Manager: sara.rostlund@chem.lu.se | 2023-08-29